Science

Research, discovery, and the natural world.

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A guide to the Nature Index

Nature, Published online: 29 July 2026; doi:10.1038/d41586-026-02183-3A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com.

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Intestinal stem cells count self-renewal divisions to switch multipotency

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10814-yIn Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing an enteroendocrine mother cell every ninth division.

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Cretaceous zhelestid mammals are zalambdalestoids

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10861-5New Mongolian fossil evidence shows zhelestids were not placental-like herbivore relatives, but a dental variant within Zalambdalestoidea, with distinctive molars alongside zalambdalestid skull and limb traits.

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Miniaturizing and modifying natural proteins with Raygun

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10842-8Probabilistic sequence encoding from language model embeddings within a generative AI framework enables protein miniaturization, modification and augmentation while maintaining native architecture and functional integrity.

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Photocatalytic water splitting by 2D polymer with out-of-plane carrier flow

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10866-0A strategy using polymeric carbon nitride crystals induces out-of-plane carrier migration by means of internal electric fields applied on facet-selective nanofilms placed on polymer photocatalysts, increasing the apparent quantum efficiency for overall water splitting.

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In situ structures of plant photosystem supercomplexes

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10847-3The cryo‑EM structure of the Oryza sativa photosystem II–light harvesting complex II supercomplex in its native membrane reveals the intact plant photosystem architecture, retaining physiologically relevant proteins and lipids that are otherwise lost during purification.

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Octahedral-coordinated Co<sub>3</sub>O<sub>4</sub> for water electrolysis in acid

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10851-7A new trigonal-phase Co3O4 manufactured using a vacuum-mediated molten-alkali mechanochemical method is described, demonstrating edge-shared octahedral coordination and achieving lower overpotential than spinel-type Co3O4 in the acidic oxygen evolution reaction, with reduced dissolution of cobalt.

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Earliest siphuncle-bearing cephalopod from the early Cambrian

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10868-yEarly Cambrian Eoceras shaanxiense gen. et sp. nov. preserves septa and a segmented tube resembling a primordial siphuncle, extending cephalopod origins and revealing early assembly of chambered shells used for buoyancy regulation.

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Plasmonic metamaterial time crystal

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10825-9A plasmonic metamaterial driven at terahertz frequencies achieves strong, ultrafast temporal modulation and shows a transition to the photonic time crystal regime with reduced plasmonic losses.